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Evolutionary Diversification of Insect Innexins
Phylogenetic analysis of insect innexins supported the hypothesis that six major clades of insect innexins arose by gene duplication prior to the origin of the endopterygote insects. Within one of the six clades (the Zpg Clade), two independent gene duplication events were inferred to have occurred...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634128/ https://www.ncbi.nlm.nih.gov/pubmed/25502029 http://dx.doi.org/10.1093/jisesa/ieu083 |
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author | Hughes, Austin L. |
author_facet | Hughes, Austin L. |
author_sort | Hughes, Austin L. |
collection | PubMed |
description | Phylogenetic analysis of insect innexins supported the hypothesis that six major clades of insect innexins arose by gene duplication prior to the origin of the endopterygote insects. Within one of the six clades (the Zpg Clade), two independent gene duplication events were inferred to have occurred in the lineage of Drosophila , after the most recent common ancestor of the dipteran families Culicidae and Drosophilidae. The relationships among this clades were poorly resolved, except for a sister relationship between ShakB and Ogre. Gene expression data from FlyAtlas supported the hypothesis that the latter gene duplication events gave rise to functional differentiation, with Zpg showing a high level of expression in ovary, and Inx5 and Inx6 showing a high level of expression in testis. Because unduplicated members of this clade in Bombyx mori and Anopheles gambiae showed high levels of expression in both ovary and tests, the expression patterns of the Drosophila members of this clade provide evidence of subdivision of an ancestral gene function after gene duplication. |
format | Online Article Text |
id | pubmed-5634128 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56341282018-04-05 Evolutionary Diversification of Insect Innexins Hughes, Austin L. J Insect Sci Research Phylogenetic analysis of insect innexins supported the hypothesis that six major clades of insect innexins arose by gene duplication prior to the origin of the endopterygote insects. Within one of the six clades (the Zpg Clade), two independent gene duplication events were inferred to have occurred in the lineage of Drosophila , after the most recent common ancestor of the dipteran families Culicidae and Drosophilidae. The relationships among this clades were poorly resolved, except for a sister relationship between ShakB and Ogre. Gene expression data from FlyAtlas supported the hypothesis that the latter gene duplication events gave rise to functional differentiation, with Zpg showing a high level of expression in ovary, and Inx5 and Inx6 showing a high level of expression in testis. Because unduplicated members of this clade in Bombyx mori and Anopheles gambiae showed high levels of expression in both ovary and tests, the expression patterns of the Drosophila members of this clade provide evidence of subdivision of an ancestral gene function after gene duplication. Oxford University Press 2014-01-01 /pmc/articles/PMC5634128/ /pubmed/25502029 http://dx.doi.org/10.1093/jisesa/ieu083 Text en © The Author 2014. Published by Oxford University Press on behalf of the Entomological Society of America. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Research Hughes, Austin L. Evolutionary Diversification of Insect Innexins |
title | Evolutionary Diversification of Insect Innexins |
title_full | Evolutionary Diversification of Insect Innexins |
title_fullStr | Evolutionary Diversification of Insect Innexins |
title_full_unstemmed | Evolutionary Diversification of Insect Innexins |
title_short | Evolutionary Diversification of Insect Innexins |
title_sort | evolutionary diversification of insect innexins |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634128/ https://www.ncbi.nlm.nih.gov/pubmed/25502029 http://dx.doi.org/10.1093/jisesa/ieu083 |
work_keys_str_mv | AT hughesaustinl evolutionarydiversificationofinsectinnexins |