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Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway

BACKGROUND: Trimethylamine‐N‐oxide (TMAO) has recently been identified as a novel and independent risk factor for promoting atherosclerosis through inducing vascular inflammation. However, the exact mechanism is currently unclear. Studies have established a central role of nucleotide‐binding oligome...

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Detalles Bibliográficos
Autores principales:	Chen, Ming‐liang, Zhu, Xiao‐hui, Ran, Li, Lang, He‐dong, Yi, Long, Mi, Man‐tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634285/ https://www.ncbi.nlm.nih.gov/pubmed/28871042 http://dx.doi.org/10.1161/JAHA.117.006347

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