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Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview

BACKGROUND: Coronary artery perforation (CAP) is a potentially lethal complication of percutaneous coronary intervention. We report on the incidence, clinical characteristics, and management of iatrogenic coronary perforations based on an 11‐year single‐center experience. METHODS AND RESULTS: From F...

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Autores principales: Lemmert, Miguel E., van Bommel, Rutger J., Diletti, Roberto, Wilschut, Jeroen M., de Jaegere, Peter P., Zijlstra, F., Daemen, Joost, Van Mieghem, Nicolas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634316/
https://www.ncbi.nlm.nih.gov/pubmed/28939719
http://dx.doi.org/10.1161/JAHA.117.007049
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author Lemmert, Miguel E.
van Bommel, Rutger J.
Diletti, Roberto
Wilschut, Jeroen M.
de Jaegere, Peter P.
Zijlstra, F.
Daemen, Joost
Van Mieghem, Nicolas M.
author_facet Lemmert, Miguel E.
van Bommel, Rutger J.
Diletti, Roberto
Wilschut, Jeroen M.
de Jaegere, Peter P.
Zijlstra, F.
Daemen, Joost
Van Mieghem, Nicolas M.
author_sort Lemmert, Miguel E.
collection PubMed
description BACKGROUND: Coronary artery perforation (CAP) is a potentially lethal complication of percutaneous coronary intervention. We report on the incidence, clinical characteristics, and management of iatrogenic coronary perforations based on an 11‐year single‐center experience. METHODS AND RESULTS: From February 9, 2005, through November 20, 2016, 150 CAP cases were identified from our percutaneous coronary intervention database of 21 212 procedures (0.71%). Mean age of CAP patients was 66±11 years, and 62.7% were male. Treated lesion type was B2/C in 94.6%, and 31.3% were chronic total occlusions. Nonworkhorse guidewires were applied in 74.3%. CAP types were Ellis type I in 2.9%, Ellis type II in 40.4%, Ellis type III in 54.8%, and Ellis type III cavity spilling in 1.9%. CAP treatment was conservative (including prolonged balloon inflation) in 73.3%. Covered stents, coiling, and fat embolization were used in 24.0%, 0.7%, and 2.0%, respectively. Pericardiocentesis for tamponade was required for 72 patients (48.0%), of whom 28 were initially unrecognized. Twelve patients (12.7%) required emergency cardiac surgery to alleviate tamponade. Periprocedural myocardial infarction occurred in 34.0%, and in‐hospital all‐cause mortality was 8.0%. All‐cause mortality accrued to 10.7% at 30 days and 17.8% at 1 year. CONCLUSIONS: CAP is a rare complication of percutaneous coronary intervention, but morbidity and mortality are considerable. Early recognition and adequate management are of paramount importance.
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spelling pubmed-56343162017-10-18 Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview Lemmert, Miguel E. van Bommel, Rutger J. Diletti, Roberto Wilschut, Jeroen M. de Jaegere, Peter P. Zijlstra, F. Daemen, Joost Van Mieghem, Nicolas M. J Am Heart Assoc Original Research BACKGROUND: Coronary artery perforation (CAP) is a potentially lethal complication of percutaneous coronary intervention. We report on the incidence, clinical characteristics, and management of iatrogenic coronary perforations based on an 11‐year single‐center experience. METHODS AND RESULTS: From February 9, 2005, through November 20, 2016, 150 CAP cases were identified from our percutaneous coronary intervention database of 21 212 procedures (0.71%). Mean age of CAP patients was 66±11 years, and 62.7% were male. Treated lesion type was B2/C in 94.6%, and 31.3% were chronic total occlusions. Nonworkhorse guidewires were applied in 74.3%. CAP types were Ellis type I in 2.9%, Ellis type II in 40.4%, Ellis type III in 54.8%, and Ellis type III cavity spilling in 1.9%. CAP treatment was conservative (including prolonged balloon inflation) in 73.3%. Covered stents, coiling, and fat embolization were used in 24.0%, 0.7%, and 2.0%, respectively. Pericardiocentesis for tamponade was required for 72 patients (48.0%), of whom 28 were initially unrecognized. Twelve patients (12.7%) required emergency cardiac surgery to alleviate tamponade. Periprocedural myocardial infarction occurred in 34.0%, and in‐hospital all‐cause mortality was 8.0%. All‐cause mortality accrued to 10.7% at 30 days and 17.8% at 1 year. CONCLUSIONS: CAP is a rare complication of percutaneous coronary intervention, but morbidity and mortality are considerable. Early recognition and adequate management are of paramount importance. John Wiley and Sons Inc. 2017-09-22 /pmc/articles/PMC5634316/ /pubmed/28939719 http://dx.doi.org/10.1161/JAHA.117.007049 Text en © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Lemmert, Miguel E.
van Bommel, Rutger J.
Diletti, Roberto
Wilschut, Jeroen M.
de Jaegere, Peter P.
Zijlstra, F.
Daemen, Joost
Van Mieghem, Nicolas M.
Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview
title Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview
title_full Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview
title_fullStr Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview
title_full_unstemmed Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview
title_short Clinical Characteristics and Management of Coronary Artery Perforations: A Single‐Center 11‐Year Experience and Practical Overview
title_sort clinical characteristics and management of coronary artery perforations: a single‐center 11‐year experience and practical overview
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634316/
https://www.ncbi.nlm.nih.gov/pubmed/28939719
http://dx.doi.org/10.1161/JAHA.117.007049
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