Cargando…
Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species
Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) encode multifunctional papain-like proteases (PLPs) that have the ability to process the viral polyprotein to facilitate RNA replication and antagonize the host innate immune response...
Autores principales: | Daczkowski, Courtney M., Dzimianski, John V., Clasman, Jozlyn R., Goodwin, Octavia, Mesecar, Andrew D., Pegan, Scott D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634334/ https://www.ncbi.nlm.nih.gov/pubmed/28438633 http://dx.doi.org/10.1016/j.jmb.2017.04.011 |
Ejemplares similares
-
Structure of interferon‐stimulated gene product 15 (ISG15) from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement
por: Langley, Caroline, et al.
Publicado: (2019) -
Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease
por: Clasman, Jozlyn R., et al.
Publicado: (2020) -
X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design
por: Clasman, Jozlyn R., et al.
Publicado: (2017) -
Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity
por: Dzimianski, John V., et al.
Publicado: (2019) -
Catalytic function and substrate specificity of alpha and beta coronavirus papain-like proteases: targeting human NL63, SARS-CoV and SARS-CoV-2 (Covid-19) with designed inhibitors
por: Chapman, Mackenzie E., et al.
Publicado: (2022)