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Autopsy findings of miliary tuberculosis in a renal transplant recipient
Miliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive tr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
São Paulo, SP: Universidade de São Paulo, Hospital Universitário
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634428/ https://www.ncbi.nlm.nih.gov/pubmed/29043204 http://dx.doi.org/10.4322/acr.2017.026 |
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author | Shergill, Khushdeep Shelly, Divya G, Manoj Kumar, Ritu Ranjan |
author_facet | Shergill, Khushdeep Shelly, Divya G, Manoj Kumar, Ritu Ranjan |
author_sort | Shergill, Khushdeep |
collection | PubMed |
description | Miliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive treatment at the earliest possible time. However, a considerable number of cases are missed ante-mortem. We discuss the case of a 32-year-old immunocompromised, non-HIV patient with an ante-mortem diagnosis of pulmonary TB. However, multiple organ involvement by Mycobacterium tuberculosis was demonstrated on autopsy. This case highlights the role of autopsy as a research and learning tool, and prudential clinico-pathologic correlation, which will improve clinical outcomes in the future. |
format | Online Article Text |
id | pubmed-5634428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | São Paulo, SP: Universidade de São Paulo, Hospital Universitário |
record_format | MEDLINE/PubMed |
spelling | pubmed-56344282017-10-17 Autopsy findings of miliary tuberculosis in a renal transplant recipient Shergill, Khushdeep Shelly, Divya G, Manoj Kumar, Ritu Ranjan Autops Case Rep Article / Autopsy Case Report Miliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive treatment at the earliest possible time. However, a considerable number of cases are missed ante-mortem. We discuss the case of a 32-year-old immunocompromised, non-HIV patient with an ante-mortem diagnosis of pulmonary TB. However, multiple organ involvement by Mycobacterium tuberculosis was demonstrated on autopsy. This case highlights the role of autopsy as a research and learning tool, and prudential clinico-pathologic correlation, which will improve clinical outcomes in the future. São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2017-09-30 /pmc/articles/PMC5634428/ /pubmed/29043204 http://dx.doi.org/10.4322/acr.2017.026 Text en Autopsy and Case Reports. ISSN 2236-1960. Copyright © 2017. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the article is properly cited. |
spellingShingle | Article / Autopsy Case Report Shergill, Khushdeep Shelly, Divya G, Manoj Kumar, Ritu Ranjan Autopsy findings of miliary tuberculosis in a renal transplant recipient |
title | Autopsy findings of miliary tuberculosis in a renal transplant recipient |
title_full | Autopsy findings of miliary tuberculosis in a renal transplant recipient |
title_fullStr | Autopsy findings of miliary tuberculosis in a renal transplant recipient |
title_full_unstemmed | Autopsy findings of miliary tuberculosis in a renal transplant recipient |
title_short | Autopsy findings of miliary tuberculosis in a renal transplant recipient |
title_sort | autopsy findings of miliary tuberculosis in a renal transplant recipient |
topic | Article / Autopsy Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634428/ https://www.ncbi.nlm.nih.gov/pubmed/29043204 http://dx.doi.org/10.4322/acr.2017.026 |
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