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Autopsy findings of miliary tuberculosis in a renal transplant recipient

Miliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive tr...

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Autores principales: Shergill, Khushdeep, Shelly, Divya, G, Manoj, Kumar, Ritu Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634428/
https://www.ncbi.nlm.nih.gov/pubmed/29043204
http://dx.doi.org/10.4322/acr.2017.026
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author Shergill, Khushdeep
Shelly, Divya
G, Manoj
Kumar, Ritu Ranjan
author_facet Shergill, Khushdeep
Shelly, Divya
G, Manoj
Kumar, Ritu Ranjan
author_sort Shergill, Khushdeep
collection PubMed
description Miliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive treatment at the earliest possible time. However, a considerable number of cases are missed ante-mortem. We discuss the case of a 32-year-old immunocompromised, non-HIV patient with an ante-mortem diagnosis of pulmonary TB. However, multiple organ involvement by Mycobacterium tuberculosis was demonstrated on autopsy. This case highlights the role of autopsy as a research and learning tool, and prudential clinico-pathologic correlation, which will improve clinical outcomes in the future.
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spelling pubmed-56344282017-10-17 Autopsy findings of miliary tuberculosis in a renal transplant recipient Shergill, Khushdeep Shelly, Divya G, Manoj Kumar, Ritu Ranjan Autops Case Rep Article / Autopsy Case Report Miliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive treatment at the earliest possible time. However, a considerable number of cases are missed ante-mortem. We discuss the case of a 32-year-old immunocompromised, non-HIV patient with an ante-mortem diagnosis of pulmonary TB. However, multiple organ involvement by Mycobacterium tuberculosis was demonstrated on autopsy. This case highlights the role of autopsy as a research and learning tool, and prudential clinico-pathologic correlation, which will improve clinical outcomes in the future. São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2017-09-30 /pmc/articles/PMC5634428/ /pubmed/29043204 http://dx.doi.org/10.4322/acr.2017.026 Text en Autopsy and Case Reports. ISSN 2236-1960. Copyright © 2017. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the article is properly cited.
spellingShingle Article / Autopsy Case Report
Shergill, Khushdeep
Shelly, Divya
G, Manoj
Kumar, Ritu Ranjan
Autopsy findings of miliary tuberculosis in a renal transplant recipient
title Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_full Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_fullStr Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_full_unstemmed Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_short Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_sort autopsy findings of miliary tuberculosis in a renal transplant recipient
topic Article / Autopsy Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634428/
https://www.ncbi.nlm.nih.gov/pubmed/29043204
http://dx.doi.org/10.4322/acr.2017.026
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