MDSCs are induced after experimental blunt chest trauma and subsequently alter antigen-specific T cell responses

Severe blunt chest trauma (TxT) induces a strong inflammatory response with posttraumatic immune suppression pointing to an impaired adaptive immune response. Since CD11b(+)Gr-1(+)-expressing myeloid-derived suppressor cells (MDSCs) are induced after inflammation and suppress T cell responses, MDSC...

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Detalles Bibliográficos
Autores principales: Hüsecken, Yvonne, Muche, Sylvia, Kustermann, Monika, Klingspor, Malena, Palmer, Annette, Braumüller, Sonja, Huber-Lang, Markus, Debatin, Klaus-Michael, Strauss, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634472/
https://www.ncbi.nlm.nih.gov/pubmed/28993671
http://dx.doi.org/10.1038/s41598-017-13019-6

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