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Involvement of PUF60 in Transcriptional and Post-transcriptional Regulation of Hepatitis B Virus Pregenomic RNA Expression

Here we identified PUF60, a splicing factor and a U2 small nuclear ribonucleoprotein auxiliary factor, as a versatile regulator of transcriptional and post-transcriptional steps in expression of hepatitis B virus (HBV) 3.5 kb, precore plus pregenomic RNA. We demonstrate that PUF60 is involved in: 1)...

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Detalles Bibliográficos
Autores principales: Sun, Suofeng, Nakashima, Kenji, Ito, Masahiko, Li, Yuan, Chida, Takeshi, Takahashi, Hirotaka, Watashi, Koichi, Sawasaki, Tatsuya, Wakita, Takaji, Suzuki, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634508/
https://www.ncbi.nlm.nih.gov/pubmed/28993636
http://dx.doi.org/10.1038/s41598-017-12497-y