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Life-Threatening Irinotecan-Induced Toxicity in an Adult Patient with Alveolar Rhabdomyosarcoma: The Role of a UGT1A1 Polymorphism

Alveolar rhabdomyosarcoma (AR) in adult patients is an exceptional malignancy. Management of AR is based on (neo)adjuvant chemotherapy combining ifosfamide, vincristine, and actinomycin D and local curative-intent surgery/radiotherapy. In cases of relapsing AR, the combination of temozolomide/irinot...

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Detalles Bibliográficos
Autores principales:	Jannin, Arnaud, Hennart, Benjamin, Adenis, Antoine, Chauffert, Bruno, Penel, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634569/ https://www.ncbi.nlm.nih.gov/pubmed/29098099 http://dx.doi.org/10.1155/2017/2683478

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