A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect

Cancer cells share several metabolic traits, including aerobic production of lactate from glucose (Warburg effect), extensive glutamine utilization and impaired mitochondrial electron flow. It is still unclear how these metabolic rearrangements, which may involve different molecular events in differ...

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Detalles Bibliográficos
Autores principales: Damiani, Chiara, Colombo, Riccardo, Gaglio, Daniela, Mastroianni, Fabrizia, Pescini, Dario, Westerhoff, Hans Victor, Mauri, Giancarlo, Vanoni, Marco, Alberghina, Lilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634631/
https://www.ncbi.nlm.nih.gov/pubmed/28957320
http://dx.doi.org/10.1371/journal.pcbi.1005758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634631/
https://www.ncbi.nlm.nih.gov/pubmed/28957320
http://dx.doi.org/10.1371/journal.pcbi.1005758

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