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PNLDC1 is essential for piRNA 3′ end trimming and transposon silencing during spermatogenesis in mice
Piwi-interacting RNAs are small regulatory RNAs with key roles in transposon silencing and regulation of gametogenesis. The production of mature piwi-interacting RNAs requires a critical step of trimming piwi-interacting RNA intermediates to achieve optimally sized piwi-interacting RNAs. The poly(A)...
Autores principales: | Ding, Deqiang, Liu, Jiali, Dong, Kunzhe, Midic, Uros, Hess, Rex A., Xie, Huirong, Demireva, Elena Y., Chen, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635004/ https://www.ncbi.nlm.nih.gov/pubmed/29018194 http://dx.doi.org/10.1038/s41467-017-00854-4 |
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