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Sodium fluorocitrate having protective effect on palmitate-induced beta cell death improves hyperglycemia in diabetic db/db mice
Beta cell loss and insulin resistance play roles in the pathogenesis of type 2 diabetes. Elevated levels of free fatty acids in plasma might contribute to the loss of beta cells. The objective of this study was to find a chemical that could protect against palmitate-induced beta cell death and inves...
Autores principales: | Jung, Ik-Rak, Choi, Sung-E., Hong, Seung A., Hwang, Yoonjung, Kang, Yup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635019/ https://www.ncbi.nlm.nih.gov/pubmed/29018279 http://dx.doi.org/10.1038/s41598-017-13365-5 |
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