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Mitochondrial Bioenergetics Is Altered in Fibroblasts from Patients with Sporadic Alzheimer's Disease

The identification of an early biomarker to diagnose Alzheimer's disease (AD) remains a challenge. Neuropathological studies in animal and AD patients have shown that mitochondrial dysfunction is a hallmark of the development of the disease. Current studies suggest the use of peripheral tissues...

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Detalles Bibliográficos
Autores principales: Pérez, María J., Ponce, Daniela P., Osorio-Fuentealba, Cesar, Behrens, Maria I., Quintanilla, Rodrigo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635042/
https://www.ncbi.nlm.nih.gov/pubmed/29056898
http://dx.doi.org/10.3389/fnins.2017.00553