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Genetic status of KRAS modulates the role of Neuropilin-1 in tumorigenesis

Neuropilin-1 (NRP1), a non–tyrosine kinase receptor, is overexpressed in many cancers including pancreatic and lung cancers. Inhibition of NRP1 expression, however, has differing pro-tumor vs. anti-tumor effects, depending on the cancer types. To understand the differential role of NRP1 in tumorigen...

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Detalles Bibliográficos
Autores principales:	Vivekanandhan, Sneha, Yang, Lijuan, Cao, Ying, Wang, Engfeng, Dutta, Shamit K., Sharma, Anil K., Mukhopadhyay, Debabrata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635066/ https://www.ncbi.nlm.nih.gov/pubmed/29018205 http://dx.doi.org/10.1038/s41598-017-12992-2

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