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6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury
Necroptosis is a programmed cell death pathway that has been shown to be of central pathophysiological relevance in multiple disorders (hepatitis, brain and cardiac ischemia, pancreatitis, viral infection and inflammatory diseases). Necroptosis is driven by two serine threonine kinases, RIPK1 (Recep...
Autores principales: | Delehouzé, C., Leverrier-Penna, S., Le Cann, F., Comte, A., Jacquard-Fevai, M., Delalande, O., Desban, N., Baratte, B., Gallais, I., Faurez, F., Bonnet, M. C., Hauteville, M., Goekjian, P. G., Thuillier, R., Favreau, F., Vandenabeele, P., Hauet, T., Dimanche-Boitrel, M. T., Bach, S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635128/ https://www.ncbi.nlm.nih.gov/pubmed/29018243 http://dx.doi.org/10.1038/s41598-017-12788-4 |
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