A Case of Non-Traumatic Avascular Necrosis of Femur in Case of Transfusion-Dependent Thalassemia

INTRODUCTION: Avascular necrosis of the head of femur (AVNF) has frequently been reported with sickle cell anemia but is not commonly associated with beta thalassemia. CASE REPORT: We report a case of 14-year-old male with transfusion-dependent thalassemia (TDT) and hepatitis C, who developed bilate...

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Autores principales: Mandhani, Geeta, Kalra, Manas, Narasimhan, Ramani, Khanna, V K, Mahajan, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Orthopaedic Research Group 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635184/
https://www.ncbi.nlm.nih.gov/pubmed/29051877
http://dx.doi.org/10.13107/jocr.2250-0685.796
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author Mandhani, Geeta
Kalra, Manas
Narasimhan, Ramani
Khanna, V K
Mahajan, Amita
author_facet Mandhani, Geeta
Kalra, Manas
Narasimhan, Ramani
Khanna, V K
Mahajan, Amita
author_sort Mandhani, Geeta
collection PubMed
description INTRODUCTION: Avascular necrosis of the head of femur (AVNF) has frequently been reported with sickle cell anemia but is not commonly associated with beta thalassemia. CASE REPORT: We report a case of 14-year-old male with transfusion-dependent thalassemia (TDT) and hepatitis C, who developed bilateral atraumatic AVNF requiring surgical correction. The likely etiopathogenesis and the review of literature for this uncommon finding are discussed. CONCLUSION: AVNF should be considered as a possibility in a patient with TDT presenting with hip pain. Multiple disease and treatment related factors are likely to play a key role in its causation.
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spelling pubmed-56351842017-10-19 A Case of Non-Traumatic Avascular Necrosis of Femur in Case of Transfusion-Dependent Thalassemia Mandhani, Geeta Kalra, Manas Narasimhan, Ramani Khanna, V K Mahajan, Amita J Orthop Case Rep Case Report INTRODUCTION: Avascular necrosis of the head of femur (AVNF) has frequently been reported with sickle cell anemia but is not commonly associated with beta thalassemia. CASE REPORT: We report a case of 14-year-old male with transfusion-dependent thalassemia (TDT) and hepatitis C, who developed bilateral atraumatic AVNF requiring surgical correction. The likely etiopathogenesis and the review of literature for this uncommon finding are discussed. CONCLUSION: AVNF should be considered as a possibility in a patient with TDT presenting with hip pain. Multiple disease and treatment related factors are likely to play a key role in its causation. Indian Orthopaedic Research Group 2017 /pmc/articles/PMC5635184/ /pubmed/29051877 http://dx.doi.org/10.13107/jocr.2250-0685.796 Text en Copyright: © Indian Orthopaedic Research Group http://creativecommons.org/licenses/by-nc/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mandhani, Geeta
Kalra, Manas
Narasimhan, Ramani
Khanna, V K
Mahajan, Amita
A Case of Non-Traumatic Avascular Necrosis of Femur in Case of Transfusion-Dependent Thalassemia
title A Case of Non-Traumatic Avascular Necrosis of Femur in Case of Transfusion-Dependent Thalassemia
title_full A Case of Non-Traumatic Avascular Necrosis of Femur in Case of Transfusion-Dependent Thalassemia
title_fullStr A Case of Non-Traumatic Avascular Necrosis of Femur in Case of Transfusion-Dependent Thalassemia
title_full_unstemmed A Case of Non-Traumatic Avascular Necrosis of Femur in Case of Transfusion-Dependent Thalassemia
title_short A Case of Non-Traumatic Avascular Necrosis of Femur in Case of Transfusion-Dependent Thalassemia
title_sort case of non-traumatic avascular necrosis of femur in case of transfusion-dependent thalassemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635184/
https://www.ncbi.nlm.nih.gov/pubmed/29051877
http://dx.doi.org/10.13107/jocr.2250-0685.796
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