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Role of p38–MAPK pathway in the effects of high-magnitude compression on nucleus pulposus cell senescence in a disc perfusion culture

Nucleus pulposus (NP) cell senescence is a typical pathological feature within the degenerative intervertebral disc. As a potential inducing and aggregating factor of disc degeneration, mechanical overloading affects disc biology in multiple ways. The present study was to investigate the NP cell sen...

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Detalles Bibliográficos
Autores principales: Pang, Lianglong, Li, Pei, Zhang, Ruijie, Xu, Yuan, Song, Lei, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635211/
https://www.ncbi.nlm.nih.gov/pubmed/28620118
http://dx.doi.org/10.1042/BSR20170718

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