Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome

A 39-year-old man with nephrotic syndrome was admitted due to right dorsal pain. Contrast-enhanced CT led to a diagnosis of renal vein thrombosis and segmental pulmonary thromboembolism. Treatment with heparin and warfarin was started. After 1 month, pulmonary thromboembolism recurred. Warfarin was...

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Detalles Bibliográficos
Autores principales: Shimada, Yoshitaka, Nagaba, Yasushi, Nagaba, Hide, Kamata, Mariko, Murano, Junya, Kamata, Fumi, Okina, Chikako, Nonoguchi, Hiroshi, Shimada, Hajime, Takeuchi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635304/
https://www.ncbi.nlm.nih.gov/pubmed/28794382
http://dx.doi.org/10.2169/internalmedicine.8742-16
Descripción
Sumario:A 39-year-old man with nephrotic syndrome was admitted due to right dorsal pain. Contrast-enhanced CT led to a diagnosis of renal vein thrombosis and segmental pulmonary thromboembolism. Treatment with heparin and warfarin was started. After 1 month, pulmonary thromboembolism recurred. Warfarin was switched to edoxaban, and steroid therapy was initiated, which led to the remission of nephrotic syndrome and the disappearance of renal vein thrombosis. The efficacy of edoxaban was demonstrated; however, this drug has not been routinely selected for patients with renal disease. Our results suggest that edoxaban is also effective for treating venous thrombosis patients with nephrotic syndrome.

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