Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome

A 39-year-old man with nephrotic syndrome was admitted due to right dorsal pain. Contrast-enhanced CT led to a diagnosis of renal vein thrombosis and segmental pulmonary thromboembolism. Treatment with heparin and warfarin was started. After 1 month, pulmonary thromboembolism recurred. Warfarin was...

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Autores principales: Shimada, Yoshitaka, Nagaba, Yasushi, Nagaba, Hide, Kamata, Mariko, Murano, Junya, Kamata, Fumi, Okina, Chikako, Nonoguchi, Hiroshi, Shimada, Hajime, Takeuchi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635304/
https://www.ncbi.nlm.nih.gov/pubmed/28794382
http://dx.doi.org/10.2169/internalmedicine.8742-16
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author Shimada, Yoshitaka
Nagaba, Yasushi
Nagaba, Hide
Kamata, Mariko
Murano, Junya
Kamata, Fumi
Okina, Chikako
Nonoguchi, Hiroshi
Shimada, Hajime
Takeuchi, Yasuo
author_facet Shimada, Yoshitaka
Nagaba, Yasushi
Nagaba, Hide
Kamata, Mariko
Murano, Junya
Kamata, Fumi
Okina, Chikako
Nonoguchi, Hiroshi
Shimada, Hajime
Takeuchi, Yasuo
author_sort Shimada, Yoshitaka
collection PubMed
description A 39-year-old man with nephrotic syndrome was admitted due to right dorsal pain. Contrast-enhanced CT led to a diagnosis of renal vein thrombosis and segmental pulmonary thromboembolism. Treatment with heparin and warfarin was started. After 1 month, pulmonary thromboembolism recurred. Warfarin was switched to edoxaban, and steroid therapy was initiated, which led to the remission of nephrotic syndrome and the disappearance of renal vein thrombosis. The efficacy of edoxaban was demonstrated; however, this drug has not been routinely selected for patients with renal disease. Our results suggest that edoxaban is also effective for treating venous thrombosis patients with nephrotic syndrome.
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spelling pubmed-56353042017-10-12 Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome Shimada, Yoshitaka Nagaba, Yasushi Nagaba, Hide Kamata, Mariko Murano, Junya Kamata, Fumi Okina, Chikako Nonoguchi, Hiroshi Shimada, Hajime Takeuchi, Yasuo Intern Med Case Report A 39-year-old man with nephrotic syndrome was admitted due to right dorsal pain. Contrast-enhanced CT led to a diagnosis of renal vein thrombosis and segmental pulmonary thromboembolism. Treatment with heparin and warfarin was started. After 1 month, pulmonary thromboembolism recurred. Warfarin was switched to edoxaban, and steroid therapy was initiated, which led to the remission of nephrotic syndrome and the disappearance of renal vein thrombosis. The efficacy of edoxaban was demonstrated; however, this drug has not been routinely selected for patients with renal disease. Our results suggest that edoxaban is also effective for treating venous thrombosis patients with nephrotic syndrome. The Japanese Society of Internal Medicine 2017-08-10 2017-09-01 /pmc/articles/PMC5635304/ /pubmed/28794382 http://dx.doi.org/10.2169/internalmedicine.8742-16 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shimada, Yoshitaka
Nagaba, Yasushi
Nagaba, Hide
Kamata, Mariko
Murano, Junya
Kamata, Fumi
Okina, Chikako
Nonoguchi, Hiroshi
Shimada, Hajime
Takeuchi, Yasuo
Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome
title Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome
title_full Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome
title_fullStr Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome
title_full_unstemmed Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome
title_short Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome
title_sort edoxaban was effective for treating renal vein thrombosis in a patient with nephrotic syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635304/
https://www.ncbi.nlm.nih.gov/pubmed/28794382
http://dx.doi.org/10.2169/internalmedicine.8742-16
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