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Fluorescent turn-on probes for wash-free mRNA imaging via covalent site-specific enzymatic labeling

Investigating the many roles RNA plays in cellular regulation and function has increased demand for tools to explore RNA tracking and localization within cells. Our recently reported RNA-TAG (transglycosylation at guanine) approach uses an RNA-modifying enzyme, tRNA-guanine transglycosylase (TGT), t...

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Detalles Bibliográficos
Autores principales: Zhou, Cun Yu, Alexander, Seth C., Devaraj, Neal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635419/
https://www.ncbi.nlm.nih.gov/pubmed/29081948
http://dx.doi.org/10.1039/c7sc03150e