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An Engineered Synthetic Pathway for Discovering Nonnatural Nonribosomal Peptides in Escherichia coli
Peptides that are synthesized independently of the ribosome in plants, fungi, and bacteria can have clinically relevant anticancer, antihemochromatosis, and antiviral activities, among many other. Despite their natural origin, discovering new natural products is challenging, and there is a need to e...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Microbiology
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635690/ https://www.ncbi.nlm.nih.gov/pubmed/29018120 http://dx.doi.org/10.1128/mBio.01474-17 |