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A microfluidic renal proximal tubule with active reabsorptive function

In the kidney, the renal proximal tubule (PT) reabsorbs solutes into the peritubular capillaries through active transport. Here, we replicate this reabsorptive function in vitro by engineering a microfluidic PT. The microfluidic PT architecture comprises a porous membrane with user-defined submicron...

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Detalles Bibliográficos
Autores principales: Vedula, Else M., Alonso, José Luis, Arnaout, M. Amin, Charest, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636065/
https://www.ncbi.nlm.nih.gov/pubmed/29020011
http://dx.doi.org/10.1371/journal.pone.0184330