Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner

Vaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important role in cell cycle regulation and its expression is altered in several human cancers. In mouse model, DUSP3 deletion prevents neo-angiogenesis and b-FGF-induced microvessel outgrowth. Considering the importance of a...

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Detalles Bibliográficos
Autores principales: Vandereyken, Maud, Jacques, Sophie, Van Overmeire, Eva, Amand, Mathieu, Rocks, Natacha, Delierneux, Céline, Singh, Pratibha, Singh, Maneesh, Ghuysen, Camille, Wathieu, Caroline, Zurashvili, Tinatin, Sounni, Nor Eddine, Moutschen, Michel, Gilles, Christine, Oury, Cécile, Cataldo, Didier, Van Ginderachter, Jo A., Rahmouni, Souad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636116/
https://www.ncbi.nlm.nih.gov/pubmed/29020102
http://dx.doi.org/10.1371/journal.pone.0185786

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