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Integrated modeling and analysis of intracellular and intercellular mechanisms in shaping the interferon response to viral infection

The interferons (IFNs) responses to viral infection are heterogeneous, while the underlying mechanisms for variability among cells are still not clear. In this study, we developed a hybrid model to systematically identify the sources of IFN induction heterogeneity. The experiment-integrated simulati...

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Detalles Bibliográficos
Autores principales:	Cai, Chunmei, Zhou, Jie, Sun, Xiaoqiang, Sun, Tingzhe, Xie, Weihong, Cui, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636135/ https://www.ncbi.nlm.nih.gov/pubmed/29020068 http://dx.doi.org/10.1371/journal.pone.0186105

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