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Comprehensive benchmarking of SNV callers for highly admixed tumor data
Precision medicine attempts to individualize cancer therapy by matching tumor-specific genetic changes with effective targeted therapies. A crucial first step in this process is the reliable identification of cancer-relevant variants, which is considerably complicated by the impurity and heterogenei...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636151/ https://www.ncbi.nlm.nih.gov/pubmed/29020110 http://dx.doi.org/10.1371/journal.pone.0186175 |