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Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates

Methylation of lysine-4 of histone H3 (H3K4me(n)) is an important regulatory factor in eukaryotic transcription. Removal of the transcriptionally activating H3K4 methylation is catalyzed by histone demethylases, including the Jumonji C (JmjC) KDM5 subfamily. The JmjC KDMs are Fe(II) and 2-oxoglutara...

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Detalles Bibliográficos
Autores principales:	Tarhonskaya, Hanna, Nowak, Radosław P., Johansson, Catrine, Szykowska, Aleksandra, Tumber, Anthony, Hancock, Rebecca L., Lang, Pauline, Flashman, Emily, Oppermann, Udo, Schofield, Christopher J., Kawamura, Akane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636616/ https://www.ncbi.nlm.nih.gov/pubmed/28827149 http://dx.doi.org/10.1016/j.jmb.2017.08.007

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