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Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [(11)C]ABP688 and PET imaging study in depression

The mechanisms of action of the rapid antidepressant effects of ketamine, an NMDA glutamate receptor antagonist, have not been fully elucidated. This study examined effects of ketamine on ligand binding to a metabotropic glutamatergic receptor (mGluR5) in individuals with major depressive disorder (...

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Detalles Bibliográficos
Autores principales:	Esterlis, Irina, DellaGioia, Nicole, Pietrzak, Robert H., Matuskey, David, Nabulsi, Nabeel, Abdallah, Chadi G., Yang, Jie, Pittenger, Christopher, Sanacora, Gerard, Krystal, John H., Parsey, Ramin V., Carson, Richard E., DeLorenzo, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636649/ https://www.ncbi.nlm.nih.gov/pubmed/28397841 http://dx.doi.org/10.1038/mp.2017.58

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