Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence

Before the onset of sprouting angiogenesis, the endothelium is prepatterned for the positioning of tip and stalk cells. Both cell identities are not static, as endothelial cells (ECs) constantly compete for the tip cell position in a dynamic fashion. Here, we show that both bone morphogenetic protei...

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Detalles Bibliográficos
Autores principales: Benn, Andreas, Hiepen, Christian, Osterland, Marc, Schütte, Christof, Zwijsen, An, Knaus, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636702/
https://www.ncbi.nlm.nih.gov/pubmed/28733457
http://dx.doi.org/10.1096/fj.201700193RR

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