Cargando…
MicroRNAs recruit eIF4E2 to repress translation of target mRNAs
MicroRNAs (miRNAs) recruit the RNA-induced silencing complex (RISC) to repress the translation of target mRNAs. While the 5′ 7-methylguanosine cap of target mRNAs has been well known to be important for miRNA repression, the underlying mechanism is not clear. Here we show that TNRC6A interacts with...
Autores principales: | Chen, Shaohong, Gao, Guangxia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636748/ https://www.ncbi.nlm.nih.gov/pubmed/28755203 http://dx.doi.org/10.1007/s13238-017-0444-0 |
Ejemplares similares
-
eIF3 targets cell proliferation mRNAs for translational activation or repression
por: Lee, Amy S.Y., et al.
Publicado: (2015) -
eIF4E exports proliferation mRNAs
por: LeBrasseur, Nicole
Publicado: (2006) -
eIF3 Interacts with Selenoprotein mRNAs
por: Hayek, Hassan, et al.
Publicado: (2022) -
Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing
por: Kamenska, Anastasiia, et al.
Publicado: (2014) -
Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity
por: Yourik, Paul, et al.
Publicado: (2017)