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The role of α(1)- and α(2)-adrenoceptor subtypes in the vasopressor responses induced by dihydroergotamine in ritanserin-pretreated pithed rats
BACKGROUND: Dihydroergotamine (DHE) is an acute antimigraine agent that displays affinity for dopamine D(2)-like receptors, serotonin 5-HT(1/2) receptors and α(1)/α(2)-adrenoceptors. Since activation of vascular α(1)/α(2)-adrenoceptors results in systemic vasopressor responses, the purpose of this s...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Milan
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636772/ https://www.ncbi.nlm.nih.gov/pubmed/29022279 http://dx.doi.org/10.1186/s10194-017-0812-4 |