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High-throughput screens using photo-highlighting discover BMP signaling in mitochondrial lipid oxidation

High-throughput screens at microscopic resolution can uncover molecular mechanisms of cellular dynamics, but remain technically challenging in live multicellular organisms. Here we present a genetic screening method using photo-highlighting for candidate selection on microscopes. We apply this metho...

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Detalles Bibliográficos
Autores principales: Yu, Yong, Mutlu, Ayse Sena, Liu, Harrison, Wang, Meng C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636786/
https://www.ncbi.nlm.nih.gov/pubmed/29021566
http://dx.doi.org/10.1038/s41467-017-00944-3