The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

Obesity and elevated circulating cholesterol are risk factors for breast cancer recurrence, while the use of statins, cholesterol biosynthesis inhibitors widely used for treating hypercholesterolemia, is associated with improved disease-free survival. Here, we show that cholesterol mediates the meta...

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Detalles Bibliográficos
Autores principales: Baek, Amy E., Yu, Yen-Rei A., He, Sisi, Wardell, Suzanne E., Chang, Ching-Yi, Kwon, Sanghoon, Pillai, Ruchita V., McDowell, Hannah B., Thompson, J. Will, Dubois, Laura G., Sullivan, Patrick M., Kemper, Jongsook K., Gunn, Michael D., McDonnell, Donald P., Nelson, Erik R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636879/
https://www.ncbi.nlm.nih.gov/pubmed/29021522
http://dx.doi.org/10.1038/s41467-017-00910-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636879/
https://www.ncbi.nlm.nih.gov/pubmed/29021522
http://dx.doi.org/10.1038/s41467-017-00910-z

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