Monocyte-lymphocyte cross-communication via soluble CD163 directly links innate immune system activation and adaptive immune system suppression following ischemic stroke

CD163 is a scavenger receptor expressed on innate immune cell populations which can be shed from the plasma membrane via the metalloprotease ADAM17 to generate a soluble peptide with lympho-inhibitory properties. The purpose of this study was to investigate CD163 as a possible effector of stroke-ind...

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Detalles Bibliográficos
Autores principales: O’Connell, Grant C., Tennant, Connie S., Lucke-Wold, Noelle, Kabbani, Yasser, Tarabishy, Abdul R., Chantler, Paul D., Barr, Taura L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636885/
https://www.ncbi.nlm.nih.gov/pubmed/29021532
http://dx.doi.org/10.1038/s41598-017-13291-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636885/
https://www.ncbi.nlm.nih.gov/pubmed/29021532
http://dx.doi.org/10.1038/s41598-017-13291-6

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