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Deficiency of peroxiredoxin 6 or inhibition of its phospholipase A(2) activity impair the in vitro sperm fertilizing competence in mice

Prdx6 (−/−) male mice are subfertile, and the deficiency or inactivation of Peroxiredoxins (PRDXs) is associated with human male infertility. We elucidate the impact of the lack of PRDX6 or inhibition of its calcium-independent phospholipase A(2) (Ca(2+)-iPLA(2)) activity by MJ33 on fertilization co...

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Detalles Bibliográficos
Autores principales:	Moawad, Adel R., Fernandez, Maria C., Scarlata, Eleonora, Dodia, Chandra, Feinstein, Sheldon I., Fisher, Aron B., O’Flaherty, Cristian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636886/ https://www.ncbi.nlm.nih.gov/pubmed/29021631 http://dx.doi.org/10.1038/s41598-017-13411-2

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