Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis

Postmenopausal osteoporosis (POMP) is a public health problem characterized by decreased bone density and increased fracture risk. Over-activated osteoclastogenesis plays a vital role in POMP. Here we developed a novel bioactive compound MASM (M19) based on sophocarpine. Although it showed no signif...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Zhi, Xin, Cao, Liehu, Weng, Weizong, Pan, Panpan, Hu, Honggang, Liu, Chao, Zhao, Qingjie, Zhou, Qirong, Cui, Jin, Su, Jiacan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636967/
https://www.ncbi.nlm.nih.gov/pubmed/28880271
http://dx.doi.org/10.1038/cddis.2017.394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636967/
https://www.ncbi.nlm.nih.gov/pubmed/28880271
http://dx.doi.org/10.1038/cddis.2017.394

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