Cargando…

ANGPTL4 mediates the protective role of PPARγ activators in the pathogenesis of preeclampsia

Peroxisome proliferator-activated receptor γ (PPARγ) has been shown to be a therapeutic target for preeclampsia (PE). Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional secretory protein involved in regulating lipid metabolism and angiogenesis in various tissues. However, the expression of P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Lei, Zhuang, Xu, Jiang, Meng, Guan, Fei, Fu, Qin, Lin, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636970/ https://www.ncbi.nlm.nih.gov/pubmed/28933788 http://dx.doi.org/10.1038/cddis.2017.419

Ejemplares similares

ANGPTL4 suppresses the profibrogenic functions of atrial fibroblasts induced by angiotensin II by up-regulating PPARγ
por: Zhu, Xi, et al.
Publicado: (2023)

PPARβ/δ recruits NCOR and regulates transcription reinitiation of ANGPTL4
por: Legrand, Nathalie, et al.
Publicado: (2019)

C1431T Variant of PPARγ Is Associated with Preeclampsia in Pregnant Women
por: Liu, Fulin, et al.
Publicado: (2021)

The Potential for Placental Activation of PPARγ to Improve the Angiogenic Profile in Preeclampsia
por: Grimaldi, Brooke, et al.
Publicado: (2022)

Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway
por: La Paglia, Laura, et al.
Publicado: (2017)

ANGPTL4 Attenuates Ang II-Induced Atrial Fibrillation and Fibrosis in Mice via PPAR Pathway
por: Zhu, Xi, et al.
Publicado: (2021)

Dual role of ANGPTL4 in inflammation
por: Zuo, Yuyue, et al.
Publicado: (2023)

Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4
por: Landfors, Fredrik, et al.
Publicado: (2022)

Understanding PPARγ and Its Agonists on Trophoblast Differentiation and Invasion: Potential Therapeutic Targets for Gestational Diabetes Mellitus and Preeclampsia
por: Qin, Yushu, et al.
Publicado: (2023)

The preventive effect of low-dose aspirin in a PPAR-γ antagonist treated mouse model of preeclampsia
por: Guo, Yongbing, et al.
Publicado: (2022)

Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion
por: Adhikary, T, et al.
Publicado: (2013)

Protective Actions of PPAR-γ Activation in Renal Endothelium
por: Westerweel, Peter E., et al.
Publicado: (2008)

Structures of Angptl3 and Angptl4, modulators of triglyceride levels and coronary artery disease
por: Biterova, Ekaterina, et al.
Publicado: (2018)

Circulating ANGPTL3 and ANGPTL4 levels predict coronary artery atherosclerosis severity
por: Sun, Ting, et al.
Publicado: (2021)

A new way to regulate inflammation: selective autophagic degradation of IKKγ mediated by ANGPTL8
por: Zhang, Yu, et al.
Publicado: (2018)

The Study of Angptl4-Modulated Podocyte Injury in IgA Nephropathy
por: Jia, Sha, et al.
Publicado: (2021)

A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia
por: Shu, Lijun, et al.
Publicado: (2022)

ANGPTL4/8 promotes plasmin-mediated cleavage of LPL inhibitors
por: Kersten, Sander
Publicado: (2023)

Increased ANGPTL3, 4 and ANGPTL8/betatrophin expression levels in obesity and T2D
por: Abu-Farha, Mohamed, et al.
Publicado: (2016)

Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension
por: Abu-Farha, Mohamed, et al.
Publicado: (2018)

Differential Expression of the Host Lipid Regulators ANGPTL-3 and ANGPTL-4 in HCV Infection and Treatment
por: Valiakou, Vaia, et al.
Publicado: (2021)

LncRNA ACART protects cardiomyocytes from apoptosis by activating PPAR‐γ/Bcl‐2 pathway
por: Wu, Hao, et al.
Publicado: (2019)

PPARγ signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPS
por: Samokhvalov, Victor, et al.
Publicado: (2014)

The Protective Effect of Apigenin on Myocardial Injury in Diabetic Rats mediating Activation of the PPAR-γ Pathway
por: Mahajan, Umesh B., et al.
Publicado: (2017)

PPARγ in Neuroblastoma
por: Peri, Alessandro, et al.
Publicado: (2008)

The Role of Transcription Factor PPAR-γ in the Pathogenesis of Psoriasis, Skin Cells, and Immune Cells
por: Sobolev, Vladimir V., et al.
Publicado: (2022)

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
por: Kulkarni, Ajit A., et al.
Publicado: (2012)

Dietary protein-induced hepatic IGF-1 secretion mediated by PPARγ activation
por: Wan, Xiaojuan, et al.
Publicado: (2017)

ANGPTL4-Mediated Promotion of Glycolysis Facilitates the Colonization of Fusobacterium nucleatum in Colorectal Cancer
por: Zheng, Xin, et al.
Publicado: (2021)

Circulating Angptl3 and Angptl8 Are Increased in Patients with Hypothyroidism
por: Yang, Longyan, et al.
Publicado: (2019)

Variable Changes of Circulating ANGPTL3 and ANGPTL4 in Different Obese Phenotypes: Relationship with Vasodilator Dysfunction
por: Schinzari, Francesca, et al.
Publicado: (2021)

Synergistic Antiproliferative Effects of Combined γ-Tocotrienol and PPARγ Antagonist Treatment Are Mediated through PPARγ-Independent Mechanisms in Breast Cancer Cells
por: Malaviya, Abhita, et al.
Publicado: (2014)

Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements
por: Inoue, Tsuyoshi, et al.
Publicado: (2014)

PPARα-mediated peroxisome induction compensates PPARγ-deficiency in bronchiolar club cells
por: Karnati, Srikanth, et al.
Publicado: (2018)

CXCR4 in Cancer and Its Regulation by PPARγ
por: Richard, Cynthia Lee, et al.
Publicado: (2008)

PGC-1α Protects against Hepatic Ischemia Reperfusion Injury by Activating PPARα and PPARγ and Regulating ROS Production
por: Wang, Chaoqun, et al.
Publicado: (2021)

Taurine protects against As(2)O(3)-induced autophagy in livers of rat offsprings through PPARγ pathway
por: Bai, Jie, et al.
Publicado: (2016)

PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ
por: Zhong, Yi, et al.
Publicado: (2023)

Altered expression of PPAR-γ and TRPC in neonatal rats with persistent pulmonary hypertension
por: Du, Yanna, et al.
Publicado: (2017)

ANGPTL4 Regulates Psoriasis via Modulating Hyperproliferation and Inflammation of Keratinocytes
por: Zuo, Yuyue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kcf7min6i42msvitvge92n2aia