Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male)

BACKGROUND: Allotetraploid F(1) hybrids (4nF(1)) (AABB, 4n = 148) were generated from the distant hybridization of Carassius auratus red var. (RCC) (AA, 2n = 100) (♀) × Megalobrama amblycephala (BSB) (BB, 2n = 48) (♂). It has been reported that Hox gene clusters are highly conserved among plants and...

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Autores principales: Wang, Y. D., Qin, Q. B., Yang, R., Sun, W. Z., Liu, Q. W., Huo, Y. Y., Huang, X., Tao, M., Zhang, C., Li, T., Liu, S. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637053/
https://www.ncbi.nlm.nih.gov/pubmed/29020918
http://dx.doi.org/10.1186/s12863-017-0550-2
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author Wang, Y. D.
Qin, Q. B.
Yang, R.
Sun, W. Z.
Liu, Q. W.
Huo, Y. Y.
Huang, X.
Tao, M.
Zhang, C.
Li, T.
Liu, S. J.
author_facet Wang, Y. D.
Qin, Q. B.
Yang, R.
Sun, W. Z.
Liu, Q. W.
Huo, Y. Y.
Huang, X.
Tao, M.
Zhang, C.
Li, T.
Liu, S. J.
author_sort Wang, Y. D.
collection PubMed
description BACKGROUND: Allotetraploid F(1) hybrids (4nF(1)) (AABB, 4n = 148) were generated from the distant hybridization of Carassius auratus red var. (RCC) (AA, 2n = 100) (♀) × Megalobrama amblycephala (BSB) (BB, 2n = 48) (♂). It has been reported that Hox gene clusters are highly conserved among plants and vertebrates. In this study, we investigated the genomic organization of Hox gene clusters in the allotetraploid F(1) hybrids and their parents to investigate the polyploidization process. RESULTS: There were three copies of Hox genes in the 4nF(1) hybrids, two copies in RCC and one copy in BSB. In addition, obvious variation and pseudogenization were observed in some Hox genes from 4nF(1.) CONCLUSION: Our results reveal the influence of polyploidization on the organization and evolution of Hox gene clusters in fish and also clarify some aspects of vertebrate genome evolution. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12863-017-0550-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-56370532017-10-18 Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male) Wang, Y. D. Qin, Q. B. Yang, R. Sun, W. Z. Liu, Q. W. Huo, Y. Y. Huang, X. Tao, M. Zhang, C. Li, T. Liu, S. J. BMC Genet Research Article BACKGROUND: Allotetraploid F(1) hybrids (4nF(1)) (AABB, 4n = 148) were generated from the distant hybridization of Carassius auratus red var. (RCC) (AA, 2n = 100) (♀) × Megalobrama amblycephala (BSB) (BB, 2n = 48) (♂). It has been reported that Hox gene clusters are highly conserved among plants and vertebrates. In this study, we investigated the genomic organization of Hox gene clusters in the allotetraploid F(1) hybrids and their parents to investigate the polyploidization process. RESULTS: There were three copies of Hox genes in the 4nF(1) hybrids, two copies in RCC and one copy in BSB. In addition, obvious variation and pseudogenization were observed in some Hox genes from 4nF(1.) CONCLUSION: Our results reveal the influence of polyploidization on the organization and evolution of Hox gene clusters in fish and also clarify some aspects of vertebrate genome evolution. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12863-017-0550-2) contains supplementary material, which is available to authorized users. BioMed Central 2017-10-11 /pmc/articles/PMC5637053/ /pubmed/29020918 http://dx.doi.org/10.1186/s12863-017-0550-2 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Wang, Y. D.
Qin, Q. B.
Yang, R.
Sun, W. Z.
Liu, Q. W.
Huo, Y. Y.
Huang, X.
Tao, M.
Zhang, C.
Li, T.
Liu, S. J.
Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male)
title Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male)
title_full Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male)
title_fullStr Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male)
title_full_unstemmed Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male)
title_short Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male)
title_sort hox genes reveal genomic dna variation in tetraploid hybrids derived from carassius auratus red var. (female) × megalobrama amblycephala (male)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637053/
https://www.ncbi.nlm.nih.gov/pubmed/29020918
http://dx.doi.org/10.1186/s12863-017-0550-2
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