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Catalysis of a 1,3-dipolar reaction by distorted DNA incorporating a heterobimetallic platinum(ii) and copper(ii) complex

A novel catalytic system based on covalently modified DNA is described. This catalyst promotes 1,3-dipolar reactions between azomethine ylides and maleimides. The catalytic system is based on the distortion of the double helix of DNA by means of the formation of Pt(ii) adducts with guanine units. Th...

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Detalles Bibliográficos
Autores principales:	Rivilla, Iván, de Cózar, Abel, Schäfer, Thomas, Hernandez, Frank J., Bittner, Alexander M., Eleta-Lopez, Aitziber, Aboudzadeh, Ali, Santos, José I., Miranda, José I., Cossío, Fernando P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637124/ https://www.ncbi.nlm.nih.gov/pubmed/29147531 http://dx.doi.org/10.1039/c7sc02311a

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