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Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes

During cell division, mitotic spindle microtubules segregate chromosomes by exerting forces on kinetochores. What forces drive chromosome segregation in anaphase remains a central question. The current model for anaphase in human cells includes shortening of kinetochore fibers and separation of spin...

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Detalles Bibliográficos
Autores principales: Vukušić, Kruno, Buđa, Renata, Bosilj, Agneza, Milas, Ana, Pavin, Nenad, Tolić, Iva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637169/
https://www.ncbi.nlm.nih.gov/pubmed/29017027
http://dx.doi.org/10.1016/j.devcel.2017.09.010

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