Emergent biomarker derived from next-generation sequencing to identify pain patients requiring uncommonly high opioid doses

Next-generation sequencing (NGS) provides unrestricted access to the genome, but it produces ‘big data’ exceeding in amount and complexity the classical analytical approaches. We introduce a bioinformatics-based classifying biomarker that uses emergent properties in genetics to separate pain patient...

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Detalles Bibliográficos
Autores principales: Kringel, D, Ultsch, A, Zimmermann, M, Jansen, J-P, Ilias, W, Freynhagen, R, Griessinger, N, Kopf, A, Stein, C, Doehring, A, Resch, E, Lötsch, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637232/
https://www.ncbi.nlm.nih.gov/pubmed/27139154
http://dx.doi.org/10.1038/tpj.2016.28

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