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Identify Huntington’s disease associated genes based on restricted Boltzmann machine with RNA-seq data
BACKGROUND: Predicting disease-associated genes is helpful for understanding the molecular mechanisms during the disease progression. Since the pathological mechanisms of neurodegenerative diseases are very complex, traditional statistic-based methods are not suitable for identifying key genes relat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637347/ https://www.ncbi.nlm.nih.gov/pubmed/29020921 http://dx.doi.org/10.1186/s12859-017-1859-6 |