Identification of 76 novel B1 metallo-β-lactamases through large-scale screening of genomic and metagenomic data

BACKGROUND: Metallo-β-lactamases are bacterial enzymes that provide resistance to carbapenems, the most potent class of antibiotics. These enzymes are commonly encoded on mobile genetic elements, which, together with their broad substrate spectrum and lack of clinically useful inhibitors, make them...

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Detalles Bibliográficos
Autores principales: Berglund, Fanny, Marathe, Nachiket P., Österlund, Tobias, Bengtsson-Palme, Johan, Kotsakis, Stathis, Flach, Carl-Fredrik, Larsson, D G Joakim, Kristiansson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637372/
https://www.ncbi.nlm.nih.gov/pubmed/29020980
http://dx.doi.org/10.1186/s40168-017-0353-8

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