Cargando…

Copper-catalyzed cyanothiolation to incorporate a sulfur-substituted quaternary carbon center

Sulfur-containing nitriles have important research value in the life sciences due to their diverse biological activities resulting from the sulfur and cyano functional groups. Herein, a copper-catalyzed cyanothiolation of N-tosylhydrazones with thiocyanates to generate α-arylthioalkanenitriles beari...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Yubing, Li, Xianwei, Wang, Xu, Yu, Yue, Zheng, Jia, Wu, Wanqing, Jiang, Huanfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637458/ https://www.ncbi.nlm.nih.gov/pubmed/29147532 http://dx.doi.org/10.1039/c7sc02867a

Ejemplares similares

Rh-catalyzed desymmetrization of α-quaternary centers by isomerization-hydroacylation
por: Park, Jung-Woo, et al.
Publicado: (2015)

Enantioselective [1,2]-Stevens rearrangement of thiosulfonates to construct dithio-substituted quaternary carbon centers
por: Hu, Linfeng, et al.
Publicado: (2022)

A convenient approach to difluoromethylated all-carbon quaternary centers via Ni(ii)-catalyzed enantioselective Michael addition
por: Yu, Xuan, et al.
Publicado: (2018)

Facile synthesis of isoquinolines and isoquinoline N-oxides via a copper-catalyzed intramolecular cyclization in water
por: Zhang, Lujun, et al.
Publicado: (2022)

Copper(I)-Catalyzed Synthesis of Unsymmetrical All-Carbon Bis-Quaternary Centers at the Opposing α-Carbons of Cyclohexanones
por: Malone, Joshua A., et al.
Publicado: (2022)

Iodine-catalyzed electrophilic substitution of indoles: Synthesis of (un)symmetrical diindolylmethanes with a quaternary carbon center
por: Pillaiyar, Thanigaimalai, et al.
Publicado: (2021)

Mechanistic insights into rhodium-catalyzed enantioselective allylic alkylation for quaternary stereogenic centers
por: Pareek, Monika, et al.
Publicado: (2020)

Copper-catalyzed reaction of aziridine for the synthesis of substituted imidazolidine and imidazolidinone
por: Hashimoto, Kota, et al.
Publicado: (2023)

Synergistic Brønsted/Lewis acid catalyzed aromatic alkylation with unactivated tertiary alcohols or di-tert-butylperoxide to synthesize quaternary carbon centers
por: Pan, Aaron, et al.
Publicado: (2022)

Stereospecific nucleophilic substitution at tertiary and quaternary stereocentres
por: Lanke, Veeranjaneyulu, et al.
Publicado: (2020)

Lewis Acid Catalyzed Transfer Hydromethallylation for the Construction of Quaternary Carbon Centers
por: Walker, Johannes C. L., et al.
Publicado: (2019)

Enantioselective allylic alkylation of stereodefined polysubstituted copper enolates as an entry to acyclic quaternary carbon stereocentres
por: Nairoukh, Zackaria, et al.
Publicado: (2017)

Diastereoselective synthesis of vicinal tertiary and N-substituted quaternary stereogenic centers by catalytic hydroalkylation of dienes
por: Goldfogel, Matthew J., et al.
Publicado: (2016)

Copper-catalyzed asymmetric hydrogenation of 2-substituted ketones via dynamic kinetic resolution
por: Zatolochnaya, Olga V., et al.
Publicado: (2018)

Palladium(ii)-catalyzed synthesis of dibenzothiophene derivatives via the cleavage of carbon–sulfur and carbon–hydrogen bonds
por: Tobisu, Mamoru, et al.
Publicado: (2016)

Cross-dehydrogenative coupling enables enantioselective access to CF(3)-substituted all-carbon quaternary stereocenters
por: Pan, Xiaoguang, et al.
Publicado: (2020)

Enantioselective construction of triaryl-substituted all-carbon quaternary stereocenters via organocatalytic arylation of oxindoles with azonaphthalenes
por: Chen, Pengquan, et al.
Publicado: (2023)

Chiral Brønsted acid-catalyzed intramolecular S(N)2′ reaction for enantioselective construction of a quaternary stereogenic center
por: Shimizu, Masahiro, et al.
Publicado: (2018)

Insights into the nucleophilic substitution of pyridine at an unsaturated carbon center
por: Du, Pan, et al.
Publicado: (2021)

Organocatalytic enantioselective S(N)1-type dehydrative nucleophilic substitution: access to bis(indolyl)methanes bearing quaternary carbon stereocenters
por: Zhu, Wen-Run, et al.
Publicado: (2021)

Formation of quaternary centres by copper catalysed asymmetric conjugate addition to β-substituted cyclopentenones with the aid of a quantitative structure–selectivity relationship
por: Ardkhean, Ruchuta, et al.
Publicado: (2018)

Copper-catalyzed direct transformation of simple alkynes to alkenyl nitriles via aerobic oxidative N-incorporation
por: Huang, Xiaoqiang, et al.
Publicado: (2015)

Sulfur stereogenic centers in transition-metal-catalyzed asymmetric C–H functionalization: generation and utilization
por: Liu, Wentan, et al.
Publicado: (2021)

Preparation of 1,2-substituted benzimidazoles via a copper-catalyzed three component coupling reaction
por: Yang, Weiguang, et al.
Publicado: (2021)

Chromium-catalyzed para-selective formation of quaternary carbon centers by alkylation of benzamide derivatives
por: Liu, Pei, et al.
Publicado: (2018)

Pd-catalyzed [3 + 2] cycloaddition of cyclic ketimines and trimethylenemethanes toward N-fused pyrrolidines bearing a quaternary carbon
por: Choi, Seoung-Mi, et al.
Publicado: (2021)

Nickel-catalyzed enantioselective α-heteroarylation of ketones via C–F bond activation to construct all-carbon quaternary stereocenters
por: Gu, Xiaodong, et al.
Publicado: (2022)

A more sustainable isothiocyanate synthesis by amine catalyzed sulfurization of isocyanides with elemental sulfur
por: Nickisch, R., et al.
Publicado: (2021)

Doubly stereoconvergent construction of vicinal all-carbon quaternary and tertiary stereocenters by Cu/Mg-catalyzed propargylic substitution
por: Pu, Xiang, et al.
Publicado: (2022)

Copper-catalyzed functionalization of enynes
por: Dherbassy, Quentin, et al.
Publicado: (2020)

Direct sialic acid 4-OAc substitution by nitrogen, sulfur and carbon nucleophiles with retention of stereochemistry
por: Bozzola, Tiago, et al.
Publicado: (2022)

Controlling alkyne reactivity by means of a copper-catalyzed radical reaction system for the synthesis of functionalized quaternary carbons
por: Hirata, Goki, et al.
Publicado: (2020)

Atom and step economical synthesis of acyclic quaternary centers via iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes
por: Cooper, Phillippa, et al.
Publicado: (2022)

The Challenging in silico Description of Carbon Monoxide Oxidation as Catalyzed by Molybdenum-Copper CO Dehydrogenase
por: Rovaletti, Anna, et al.
Publicado: (2019)

Synthesis of Vicinal Quaternary All-Carbon Centers via Acid-catalyzed Cycloisomerization of Neopentylic Epoxides
por: Schmid, Matthias, et al.
Publicado: (2020)

Palladium-catalyzed/copper-mediated carbon–carbon cross-coupling reaction for synthesis of 6-unsubstituted 2-aryldihydropyrimidines
por: Nishimura, Yoshio, et al.
Publicado: (2022)

Desymmetrization of cyclic 1,3-diketones via Ir-catalyzed hydrogenation: an efficient approach to cyclic hydroxy ketones with a chiral quaternary carbon
por: Gong, Quan, et al.
Publicado: (2019)

Determination of the absolute configuration of compounds bearing chiral quaternary carbon centers using the crystalline sponge method
por: Sairenji, Shiho, et al.
Publicado: (2017)

Copper-catalyzed direct alkylation of heteroarenes
por: Theunissen, Cédric, et al.
Publicado: (2017)

Copper-catalyzed enantioselective arylalkynylation of alkenes
por: Lei, Guangyue, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ikcvpglbrfl1lvkb9tpa7o13tg