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Modelling the impact of targeted anthelmintic treatment of cattle on dung fauna

The insecticidal properties of many anthelmintics pose a risk to dung fauna through the effects of drug residues in dung on the activity, oviposition and development of dung-dwelling invertebrates. Reductions in dung fauna numbers can inhibit dung degradation, which may impact biodiversity and nutri...

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Autores principales: Cooke, Andrew S., Morgan, Eric R., Dungait, Jennifer A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637707/
https://www.ncbi.nlm.nih.gov/pubmed/28843101
http://dx.doi.org/10.1016/j.etap.2017.07.012
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author Cooke, Andrew S.
Morgan, Eric R.
Dungait, Jennifer A.J.
author_facet Cooke, Andrew S.
Morgan, Eric R.
Dungait, Jennifer A.J.
author_sort Cooke, Andrew S.
collection PubMed
description The insecticidal properties of many anthelmintics pose a risk to dung fauna through the effects of drug residues in dung on the activity, oviposition and development of dung-dwelling invertebrates. Reductions in dung fauna numbers can inhibit dung degradation, which may impact biodiversity and nutrient cycling on farms. A simulation model was created to predict the impact of antiparasitic drugs on cattle dung fauna, and calibrated using published data on the dung-breeding fly Scathophaga stercoraria. This model was then tested under different effective dung drug concentrations (EC) and proportions of treated cattle (PT) to determine the impact under different application regimens. EC accounted for 12.9% of the observed variation in S. stercoraria population size, whilst PT accounted for 54.9%. The model outputs indicate that the tendency within veterinary medicine for targeted selective treatments (TST), in order to attenuate selection for drug resistance in parasite populations, will decrease the negative impacts of treatments on dung fauna populations by providing population refugia. This provides novel evidence for the benefits of TST regimens on local food webs, relative to whole-herd treatments. The model outputs were used to create a risk graph for stakeholders to use to estimate risk of anthelminthic toxicity to dung fauna.
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spelling pubmed-56377072017-10-19 Modelling the impact of targeted anthelmintic treatment of cattle on dung fauna Cooke, Andrew S. Morgan, Eric R. Dungait, Jennifer A.J. Environ Toxicol Pharmacol Article The insecticidal properties of many anthelmintics pose a risk to dung fauna through the effects of drug residues in dung on the activity, oviposition and development of dung-dwelling invertebrates. Reductions in dung fauna numbers can inhibit dung degradation, which may impact biodiversity and nutrient cycling on farms. A simulation model was created to predict the impact of antiparasitic drugs on cattle dung fauna, and calibrated using published data on the dung-breeding fly Scathophaga stercoraria. This model was then tested under different effective dung drug concentrations (EC) and proportions of treated cattle (PT) to determine the impact under different application regimens. EC accounted for 12.9% of the observed variation in S. stercoraria population size, whilst PT accounted for 54.9%. The model outputs indicate that the tendency within veterinary medicine for targeted selective treatments (TST), in order to attenuate selection for drug resistance in parasite populations, will decrease the negative impacts of treatments on dung fauna populations by providing population refugia. This provides novel evidence for the benefits of TST regimens on local food webs, relative to whole-herd treatments. The model outputs were used to create a risk graph for stakeholders to use to estimate risk of anthelminthic toxicity to dung fauna. Elsevier Science B.V 2017-10 /pmc/articles/PMC5637707/ /pubmed/28843101 http://dx.doi.org/10.1016/j.etap.2017.07.012 Text en © 2017 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cooke, Andrew S.
Morgan, Eric R.
Dungait, Jennifer A.J.
Modelling the impact of targeted anthelmintic treatment of cattle on dung fauna
title Modelling the impact of targeted anthelmintic treatment of cattle on dung fauna
title_full Modelling the impact of targeted anthelmintic treatment of cattle on dung fauna
title_fullStr Modelling the impact of targeted anthelmintic treatment of cattle on dung fauna
title_full_unstemmed Modelling the impact of targeted anthelmintic treatment of cattle on dung fauna
title_short Modelling the impact of targeted anthelmintic treatment of cattle on dung fauna
title_sort modelling the impact of targeted anthelmintic treatment of cattle on dung fauna
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637707/
https://www.ncbi.nlm.nih.gov/pubmed/28843101
http://dx.doi.org/10.1016/j.etap.2017.07.012
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