Cargando…

Salidroside Protects against MPP+-Induced Neuronal Injury through DJ-1-Nrf2 Antioxidant Pathway

Parkinson's disease (PD) is the second most common neurodegenerative disorder. We have found that salidroside (Sal) exhibited neuroprotective effects against MPP+ toxicity. However, the molecular mechanism is not fully understood. In this study, we found that Sal significantly prevented MPP+-in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Leitao, Xu, Hang, Cao, Liang, Li, Tao, Li, Ruru, Feng, Yang, Chen, Jianzong, Ma, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637855/ https://www.ncbi.nlm.nih.gov/pubmed/29234413 http://dx.doi.org/10.1155/2017/5398542

Ejemplares similares

Salidroside Protects Dopaminergic Neurons by Preserving Complex I Activity via DJ-1/Nrf2-Mediated Antioxidant Pathway
por: Li, Ruru, et al.
Publicado: (2019)

Salidroside Protects Dopaminergic Neurons by Enhancing PINK1/Parkin-Mediated Mitophagy
por: Li, Ruru, et al.
Publicado: (2019)

Salidroside Promotes the Pathological α-Synuclein Clearance Through Ubiquitin-Proteasome System in SH-SY5Y Cells
por: Li, Tao, et al.
Publicado: (2018)

Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson's Disease: Involvement of the PI3K/Akt/GSK3β Pathway
por: Zhang, Wei, et al.
Publicado: (2016)

AITC induces MRP1 expression by protecting against CS/CSE-mediated DJ-1 protein degradation via activation of the DJ-1/Nrf2 axis
por: Xu, Lingling, et al.
Publicado: (2020)

The Protection of Salidroside of the Heart against Acute Exhaustive Injury and Molecular Mechanism in Rat
por: Wang, Yunru, et al.
Publicado: (2013)

Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP(+) and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway
por: Guo, Xingfang, et al.
Publicado: (2019)

Salidroside protects against ventilation-induced lung injury by inhibiting the expression of matrix metalloproteinase-9
por: Zhang, Hui, et al.
Publicado: (2021)

Antioxidant Effects of Salidroside in the Cardiovascular System
por: Sun, Siyu, et al.
Publicado: (2020)

Polygonatum sibiricum Polysaccharides Protect against MPP-Induced Neurotoxicity via the Akt/mTOR and Nrf2 Pathways
por: Huang, Si, et al.
Publicado: (2021)

Salidroside pretreatment protects against myocardial injury induced by heat stroke in mice
por: Chen, Guo-dong, et al.
Publicado: (2019)

Pathogenic Mutation in VPS35 Impairs Its Protection against MPP(+) Cytotoxicity
por: Bi, Fangfang, et al.
Publicado: (2013)

Bacopa Protects against Neurotoxicity Induced by MPP(+) and Methamphetamine
por: Ferrucci, Michela, et al.
Publicado: (2022)

Quercetin Protects against MPP(+)/MPTP-Induced Dopaminergic Neuron Death in Parkinson's Disease by Inhibiting Ferroptosis
por: Lin, Zhi-Hao, et al.
Publicado: (2022)

Salidroside Protects Against Influenza A Virus-Induced Acute Lung Injury in Mice
por: Lu, Rufeng, et al.
Publicado: (2021)

The Protective Effects of Salidroside from Exhaustive Exercise-Induced Heart Injury by Enhancing the PGC-1 α–NRF1/NRF2 Pathway and Mitochondrial Respiratory Function in Rats
por: Ping, Zheng, et al.
Publicado: (2015)

Salidroside Protects Lipopolysaccharide-Induced Acute Lung Injury in Mice
por: Lu, Rufeng, et al.
Publicado: (2016)

The protective effect of lactoferrin on ventral mesencephalon neurons against MPP(+) is not connected with its iron binding ability
por: Wang, Jun, et al.
Publicado: (2015)

LINC00667 regulates MPP(+)‐induced neuronal injury in Parkinson’s disease
por: Huo, Xinlong, et al.
Publicado: (2022)

Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP(+) Toxicity in Neuronal Cells
por: Ho, Philip Wing-Lok, et al.
Publicado: (2009)

Involvement of the ERK pathway in the protective effects of glycyrrhizic acid against the MPP(+)-induced apoptosis of dopaminergic neuronal cells
por: TENG, LESHENG, et al.
Publicado: (2014)

DJ-1 protects retinal pericytes against high glucose-induced oxidative stress through the Nrf2 signaling pathway
por: Wang, Wanpeng, et al.
Publicado: (2020)

Paeonolum protects against MPP(+)-induced neurotoxicity in zebrafish and PC12 cells
por: Lu, Xi-Lin, et al.
Publicado: (2015)

Salidroside Protects against Cadmium-Induced Hepatotoxicity in Rats via GJIC and MAPK Pathways
por: Zou, Hui, et al.
Publicado: (2015)

The Alteration of Nasopharyngeal and Oropharyngeal Microbiota in Children with MPP and Non-MPP
por: Lu, Zhiwei, et al.
Publicado: (2017)

Salidroside Protects Against Advanced Glycation End Products-Induced Vascular Endothelial Dysfunction
por: Zhang, Peng, et al.
Publicado: (2018)

Salidroside Protects Caenorhabditis elegans Neurons from Polyglutamine-Mediated Toxicity by Reducing Oxidative Stress
por: Xiao, Lingyun, et al.
Publicado: (2014)

SOD1 and DJ-1 Converge at Nrf2 Pathway: A Clue for Antioxidant Therapeutic Potential in Neurodegeneration
por: Milani, Pamela, et al.
Publicado: (2013)

Protective Effects of a Rhodiola Crenulata Extract and Salidroside on Hippocampal Neurogenesis against Streptozotocin-Induced Neural Injury in the Rat
por: Qu, Ze-qiang, et al.
Publicado: (2012)

Salidroside Suppresses HUVECs Cell Injury Induced by Oxidative Stress through Activating the Nrf2 Signaling Pathway
por: Zhu, Yao, et al.
Publicado: (2016)

Protection of dopamine neurons by CDNF and neurturin variant N4 against MPP(+) in dissociated cultures from rat mesencephalon
por: Jaumotte, Juliann D., et al.
Publicado: (2021)

DJ-1 protects against cell death following acute cardiac ischemia–reperfusion injury
por: Dongworth, R K, et al.
Publicado: (2014)

PGK1 inhibitor CBR-470-1 protects neuronal cells from MPP(+)
por: Zheng, Jinyu, et al.
Publicado: (2020)

Salidroside protects endothelial cells against LPS-induced inflammatory injury by inhibiting NLRP3 and enhancing autophagy
por: You, Lijiao, et al.
Publicado: (2021)

Salidroside Protects Acute Kidney Injury in Septic Rats by Inhibiting Inflammation and Apoptosis
por: Fan, Heng, et al.
Publicado: (2022)

DCA Protects against Oxidation Injury Attributed to Cerebral Ischemia-Reperfusion by Regulating Glycolysis through PDK2-PDH-Nrf2 Axis
por: Zhao, Xiaoyong, et al.
Publicado: (2021)

Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/MPTP-Lesioned Dopaminergic Neurons
por: Aguirre, Pabla, et al.
Publicado: (2015)

Mechanism of salidroside against coronary artery disease by network pharmacology analysis
por: Tao, Lin, et al.
Publicado: (2023)

Salidroside protects against foam cell formation and apoptosis, possibly via the MAPK and AKT signaling pathways
por: Ni, Jing, et al.
Publicado: (2017)

Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury
por: Jeong, Hoon Jae, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_4qhqrj2psird6i3nvrs99kao8r