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The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal

Schistosomiasis is a parasitic, water-related disease that is prevalent in tropical and subtropical areas of the world, causing severe and chronic consequences especially among children. Here we study the spatial spread of this disease within a network of connected villages in the endemic region of...

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Detalles Bibliográficos
Autores principales: Ciddio, Manuela, Mari, Lorenzo, Sokolow, Susanne H., De Leo, Giulio A., Casagrandi, Renato, Gatto, Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: C.M.L. Publications ;, Springer-Verlag 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637889/
https://www.ncbi.nlm.nih.gov/pubmed/29056816
http://dx.doi.org/10.1016/j.advwatres.2016.10.012
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author Ciddio, Manuela
Mari, Lorenzo
Sokolow, Susanne H.
De Leo, Giulio A.
Casagrandi, Renato
Gatto, Marino
author_facet Ciddio, Manuela
Mari, Lorenzo
Sokolow, Susanne H.
De Leo, Giulio A.
Casagrandi, Renato
Gatto, Marino
author_sort Ciddio, Manuela
collection PubMed
description Schistosomiasis is a parasitic, water-related disease that is prevalent in tropical and subtropical areas of the world, causing severe and chronic consequences especially among children. Here we study the spatial spread of this disease within a network of connected villages in the endemic region of the Lower Basin of the Senegal River, in Senegal. The analysis is performed by means of a spatially explicit metapopulation model that couples local-scale eco-epidemiological dynamics with spatial mechanisms related to human mobility (estimated from anonymized mobile phone records), snail dispersal and hydrological transport of schistosome larvae along the main water bodies of the region. Results show that the model produces epidemiological patterns consistent with field observations, and point out the key role of spatial connectivity on the spread of the disease. These findings underline the importance of considering different transport pathways in order to elaborate disease control strategies that can be effective within a network of connected populations.
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spelling pubmed-56378892017-10-19 The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal Ciddio, Manuela Mari, Lorenzo Sokolow, Susanne H. De Leo, Giulio A. Casagrandi, Renato Gatto, Marino Adv Water Resour Article Schistosomiasis is a parasitic, water-related disease that is prevalent in tropical and subtropical areas of the world, causing severe and chronic consequences especially among children. Here we study the spatial spread of this disease within a network of connected villages in the endemic region of the Lower Basin of the Senegal River, in Senegal. The analysis is performed by means of a spatially explicit metapopulation model that couples local-scale eco-epidemiological dynamics with spatial mechanisms related to human mobility (estimated from anonymized mobile phone records), snail dispersal and hydrological transport of schistosome larvae along the main water bodies of the region. Results show that the model produces epidemiological patterns consistent with field observations, and point out the key role of spatial connectivity on the spread of the disease. These findings underline the importance of considering different transport pathways in order to elaborate disease control strategies that can be effective within a network of connected populations. C.M.L. Publications ;, Springer-Verlag 2017-10 /pmc/articles/PMC5637889/ /pubmed/29056816 http://dx.doi.org/10.1016/j.advwatres.2016.10.012 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ciddio, Manuela
Mari, Lorenzo
Sokolow, Susanne H.
De Leo, Giulio A.
Casagrandi, Renato
Gatto, Marino
The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal
title The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal
title_full The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal
title_fullStr The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal
title_full_unstemmed The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal
title_short The spatial spread of schistosomiasis: A multidimensional network model applied to Saint-Louis region, Senegal
title_sort spatial spread of schistosomiasis: a multidimensional network model applied to saint-louis region, senegal
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637889/
https://www.ncbi.nlm.nih.gov/pubmed/29056816
http://dx.doi.org/10.1016/j.advwatres.2016.10.012
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