Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions

Rapid and quantitative click functionalization of surfaces remains an interesting challenge in surface chemistry. In this regard, inverse electron demand Diels–Alder (IEDDA) reactions represent a promising metal‐free candidate. Herein, we reveal quantitative surface functionalization within 15 min....

Descripción completa

Detalles Bibliográficos
Autores principales: Sen, Rickdeb, Gahtory, Digvijay, Escorihuela, Jorge, Firet, Judith, Pujari, Sidharam P., Zuilhof, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637934/
https://www.ncbi.nlm.nih.gov/pubmed/28703436
http://dx.doi.org/10.1002/chem.201703103
Descripción
Sumario:Rapid and quantitative click functionalization of surfaces remains an interesting challenge in surface chemistry. In this regard, inverse electron demand Diels–Alder (IEDDA) reactions represent a promising metal‐free candidate. Herein, we reveal quantitative surface functionalization within 15 min. Furthermore, we report the comprehensive effects of substrate stereochemistry, surrounding microenvironment and substrate order on the reaction kinetics as obtained by surface‐bound mass spectrometry (DART‐HRMS).

Ejemplares similares