Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions

Rapid and quantitative click functionalization of surfaces remains an interesting challenge in surface chemistry. In this regard, inverse electron demand Diels–Alder (IEDDA) reactions represent a promising metal‐free candidate. Herein, we reveal quantitative surface functionalization within 15 min....

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Detalles Bibliográficos
Autores principales: Sen, Rickdeb, Gahtory, Digvijay, Escorihuela, Jorge, Firet, Judith, Pujari, Sidharam P., Zuilhof, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637934/
https://www.ncbi.nlm.nih.gov/pubmed/28703436
http://dx.doi.org/10.1002/chem.201703103
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author Sen, Rickdeb
Gahtory, Digvijay
Escorihuela, Jorge
Firet, Judith
Pujari, Sidharam P.
Zuilhof, Han
author_facet Sen, Rickdeb
Gahtory, Digvijay
Escorihuela, Jorge
Firet, Judith
Pujari, Sidharam P.
Zuilhof, Han
author_sort Sen, Rickdeb
collection PubMed
description Rapid and quantitative click functionalization of surfaces remains an interesting challenge in surface chemistry. In this regard, inverse electron demand Diels–Alder (IEDDA) reactions represent a promising metal‐free candidate. Herein, we reveal quantitative surface functionalization within 15 min. Furthermore, we report the comprehensive effects of substrate stereochemistry, surrounding microenvironment and substrate order on the reaction kinetics as obtained by surface‐bound mass spectrometry (DART‐HRMS).
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spelling pubmed-56379342017-10-25 Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions Sen, Rickdeb Gahtory, Digvijay Escorihuela, Jorge Firet, Judith Pujari, Sidharam P. Zuilhof, Han Chemistry Communications Rapid and quantitative click functionalization of surfaces remains an interesting challenge in surface chemistry. In this regard, inverse electron demand Diels–Alder (IEDDA) reactions represent a promising metal‐free candidate. Herein, we reveal quantitative surface functionalization within 15 min. Furthermore, we report the comprehensive effects of substrate stereochemistry, surrounding microenvironment and substrate order on the reaction kinetics as obtained by surface‐bound mass spectrometry (DART‐HRMS). John Wiley and Sons Inc. 2017-08-23 2017-09-21 /pmc/articles/PMC5637934/ /pubmed/28703436 http://dx.doi.org/10.1002/chem.201703103 Text en © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Communications
Sen, Rickdeb
Gahtory, Digvijay
Escorihuela, Jorge
Firet, Judith
Pujari, Sidharam P.
Zuilhof, Han
Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions
title Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions
title_full Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions
title_fullStr Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions
title_full_unstemmed Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions
title_short Approach Matters: The Kinetics of Interfacial Inverse‐Electron Demand Diels–Alder Reactions
title_sort approach matters: the kinetics of interfacial inverse‐electron demand diels–alder reactions
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637934/
https://www.ncbi.nlm.nih.gov/pubmed/28703436
http://dx.doi.org/10.1002/chem.201703103
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