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A randomized controlled phase II clinical trial comparing ONO‐4053, a novel DP1 antagonist, with a leukotriene receptor antagonist pranlukast in patients with seasonal allergic rhinitis

BACKGROUND: Prostaglandin D(2) (PGD (2)) is primarily produced by mast cells and is contributing to the nasal symptoms including nasal obstruction and rhinorrhea. OBJECTIVE: This study aimed to evaluate the efficacy and safety of a novel PGD (2) receptor 1 (DP1) antagonist, ONO‐4053, in patients wit...

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Detalles Bibliográficos
Autores principales:	Okubo, K., Hashiguchi, K., Takeda, T., Baba, K., Kitagoh, H., Miho, H., Tomomatsu, H., Yamaguchi, S., Odani, M., Yamamotoya, H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638107/ https://www.ncbi.nlm.nih.gov/pubmed/28378369 http://dx.doi.org/10.1111/all.13174

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