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Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF77_cpx) Identified among Blood Donors in Malaysia

We report here the first HIV-1 circulating recombinant form (CRF) complex identified among the blood donors in Malaysia. The CRF77_cpx mosaic genome consists of parental subtypes B′, C, and CRF01_AE and is structurally related to CRF07_BC. The identification of CRF77_cpx underlines the genetic compl...

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Autores principales: Tee, Kok Keng, Bon, Abdul Hamid, Chow, Wei Zhen, Ng, Kim Tien, Chan, Kok Gan, Kamarulzaman, Adeeba, Busch, Michael P., Takebe, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638273/
https://www.ncbi.nlm.nih.gov/pubmed/28663289
http://dx.doi.org/10.1128/genomeA.00459-17
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author Tee, Kok Keng
Bon, Abdul Hamid
Chow, Wei Zhen
Ng, Kim Tien
Chan, Kok Gan
Kamarulzaman, Adeeba
Busch, Michael P.
Takebe, Yutaka
author_facet Tee, Kok Keng
Bon, Abdul Hamid
Chow, Wei Zhen
Ng, Kim Tien
Chan, Kok Gan
Kamarulzaman, Adeeba
Busch, Michael P.
Takebe, Yutaka
author_sort Tee, Kok Keng
collection PubMed
description We report here the first HIV-1 circulating recombinant form (CRF) complex identified among the blood donors in Malaysia. The CRF77_cpx mosaic genome consists of parental subtypes B′, C, and CRF01_AE and is structurally related to CRF07_BC. The identification of CRF77_cpx underlines the genetic complexity and mobility of HIV-1 among the blood donors.
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spelling pubmed-56382732017-10-13 Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF77_cpx) Identified among Blood Donors in Malaysia Tee, Kok Keng Bon, Abdul Hamid Chow, Wei Zhen Ng, Kim Tien Chan, Kok Gan Kamarulzaman, Adeeba Busch, Michael P. Takebe, Yutaka Genome Announc Viruses We report here the first HIV-1 circulating recombinant form (CRF) complex identified among the blood donors in Malaysia. The CRF77_cpx mosaic genome consists of parental subtypes B′, C, and CRF01_AE and is structurally related to CRF07_BC. The identification of CRF77_cpx underlines the genetic complexity and mobility of HIV-1 among the blood donors. American Society for Microbiology 2017-06-29 /pmc/articles/PMC5638273/ /pubmed/28663289 http://dx.doi.org/10.1128/genomeA.00459-17 Text en Copyright © 2017 Tee et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Viruses
Tee, Kok Keng
Bon, Abdul Hamid
Chow, Wei Zhen
Ng, Kim Tien
Chan, Kok Gan
Kamarulzaman, Adeeba
Busch, Michael P.
Takebe, Yutaka
Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF77_cpx) Identified among Blood Donors in Malaysia
title Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF77_cpx) Identified among Blood Donors in Malaysia
title_full Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF77_cpx) Identified among Blood Donors in Malaysia
title_fullStr Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF77_cpx) Identified among Blood Donors in Malaysia
title_full_unstemmed Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF77_cpx) Identified among Blood Donors in Malaysia
title_short Genome Sequence of a Novel HIV-1 Circulating Recombinant Form (CRF77_cpx) Identified among Blood Donors in Malaysia
title_sort genome sequence of a novel hiv-1 circulating recombinant form (crf77_cpx) identified among blood donors in malaysia
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638273/
https://www.ncbi.nlm.nih.gov/pubmed/28663289
http://dx.doi.org/10.1128/genomeA.00459-17
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