Improved influenza viral vector based Brucella abortus vaccine induces robust B and T-cell responses and protection against Brucella melitensis infection in pregnant sheep and goats

We previously developed a potent candidate vaccine against bovine brucellosis caused by Brucella abortus using the influenza viral vector expressing Brucella Omp16 and L7/L12 proteins (Flu-BA). Our success in the Flu-BA vaccine trial in cattle and results of a pilot study in non-pregnant small rumin...

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Detalles Bibliográficos
Autores principales: Mailybayeva, Aigerim, Yespembetov, Bolat, Ryskeldinova, Sholpan, Zinina, Nadezhda, Sansyzbay, Abylai, Renukaradhya, Gourapura J., Petrovsky, Nikolai, Tabynov, Kaissar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638537/
https://www.ncbi.nlm.nih.gov/pubmed/29023541
http://dx.doi.org/10.1371/journal.pone.0186484

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